description
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Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GAGCAGCCTTTCTGCTGATTATCACACATCATGAGCTGAGTGACTGCAGCTTGCCAAATCTTTGTGTTTCTGGGTCTGACCAATTAGCTTAGTTCTTCTCCTGCCTAATTTTGAACTAGTAAAGCAAAGTGAGTCATCAGATTATGAGTTACTGTTTAAAAGAAAAATGCTGTTTATTCATGCTGAGGTGATTCAGTTCCCTCCTTCTTACAGAAGTATTTTAATTCACCCCACACTAGAAATGCAGCATCTTTGTGGACGTCTTTTTCACAAGCCTCCAAGGCTCCTTAGATTGGGTCGTTACTAAAAGTACATTAAAACACTCTTGTTTATCGAAGTATATTGATGTATTCTAAAGCTAGTAAACTTCCCTAACGTTTAATTGCCCTACAGATGCTTCTCTTGCTGTGGGT
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
저장 등급
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Motoki Fujimaki et al.
Molecular and cellular biology, 39(14) (2019-05-08)
Iron is an essential nutrient for mitochondrial metabolic processes, including mitochondrial respiration. Ferritin complexes store excess iron and protect cells from iron toxicity. Therefore, iron stored in the ferritin complex might be utilized under iron-depleted conditions. In this study, we
Changfeng Li et al.
Developmental cell, 46(4), 441-455 (2018-08-14)
Pancreatic cancer is an aggressive malignancy with changes in the tumor microenvironment. Here, we demonstrate that PINK1 and PARK2 suppressed pancreatic tumorigenesis through control of mitochondrial iron-dependent immunometabolism. Using mouse models of spontaneous pancreatic cancer, we show that depletion of Pink1 and Park2
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.