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Merck

G5013

G 418 disulfate salt

potency: ≥720 μg per mg (dried basis)

동의어(들):

Antibiotic G418

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C20H40N4O10 · 2H2SO4
CAS 번호:
Molecular Weight:
692.71
MDL number:
UNSPSC Code:
51102829
PubChem Substance ID:
NACRES:
NA.85
기술 서비스
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SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

form

powder

potency

≥720 μg per mg (dried basis)

color

white to off-white

solubility

H2O: 100 mg/mL

antibiotic activity spectrum

Gram-negative bacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

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General description

Chemical structure: aminoglycoside

Preparation Note

G418 powder is soluble in water at 100 mg/mL.

Disclaimer

The product is stable for three years when stored at 2-8°C. Aqueous solutions stored frozen at -20 to -70 °C should be stable for approximately six months.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

저장 등급

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

Yoshie Tange et al.
PLoS genetics, 8(6), e1002776-e1002776 (2012-06-28)
To identify the genes required to sustain aneuploid viability, we screened a deletion library of non-essential genes in the fission yeast Schizosaccharomyces pombe, in which most types of aneuploidy are eventually lethal to the cell. Aneuploids remain viable for a
Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5).
Matthias Geissbuehler et al.
Advances in experimental medicine and biology, 737, 263-268 (2012-01-20)
Alexandra L Petrache et al.
Frontiers in cellular neuroscience, 14, 568194-568194 (2020-12-03)
Selective negative allosteric modulators (NAMs), targeting α5 subunit-containing GABAA receptors (GABAARs) as potential therapeutic targets for disorders associated with cognitive deficits, including Alzheimer's disease (AD), continually fail clinical trials. We investigated whether this was due to the change in the
Shijia Yu et al.
Frontiers in cellular neuroscience, 14, 193-193 (2020-08-08)
Cerebral ischemic stroke is regarded as one of the most serious diseases in the human central nervous system. The secondary ischemia and reperfusion (I/R) injury increased the difficulty of treatment. Moreover, the latent molecular regulating mechanism in I/R injury is
Terezie Imrichova et al.
Aging, 11(17), 7206-7235 (2019-09-08)
Diverse stress insults trigger interactions of PML with nucleolus, however, the function of these PML nucleolar associations (PNAs) remains unclear. Here we show that during induction of DNA damage-induced senescence in human non-cancerous cells, PML accumulates at the nucleolar periphery

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