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Merck

G5422

β-Glycerophosphate disodium salt hydrate

≤1.0 mol % L-α-isomer

동의어(들):

BGP, Glycerol 2-phosphate disodium salt hydrate

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(HOCH2)2CHOP(O)(ONa)2 · xH2O
CAS 번호:
Molecular Weight:
216.04 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
212-464-3
MDL number:
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도움 문의


biological source

synthetic

Quality Level

form

powder

impurities

≤0.1% Inorganic phosphorus, ≤1.0 mol % L-α-isomer

mp

102-104 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2

InChI key

ROPZSVKNEIIIDE-UHFFFAOYSA-L

Application

β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Analysis Note

Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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