G6657

(−)-Gallocatechin

Name: (−)-Gallocatechin
Brand: SIGMA

≥98% (HPLC)

동의어(들):

(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₅H₁₄O₇

CAS 번호:

3371-27-5

Molecular Weight:

306.27

NACRES:

NA.77

PubChem Substance ID:

24895266

UNSPSC Code:

12352205

MDL number:

MFCD01632616

주요 문서

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InChI

1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15+/m1/s1

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(O)c(O)c3

InChI key

XMOCLSLCDHWDHP-DOMZBBRYSA-N

assay

≥98% (HPLC)

solubility

H₂O: 5 mg/mL (heat 2-10 min at 105C), alcohol: soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

Quality Level

200

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General description

(−)-Gallocatechin is a polyphenolic compound and one of the primary catechins present in green tea Camellia sinensis.

Application

(−)-Gallocatechin has been used as a reference standard:

for the identification of phenolic compounds present in Pineapple (Ananas comosus) using high-performance liquid chromatography (HPLC)
to evaluate the catechin profiles from Camellia sinensis green tea, white tea, and flower sample by high-performance liquid chromatography/photodiode array detection (RP-HPLC/PDAD) analysis
as a reference standard for the flavan-3-ols profiling muscadine grape hybrid varieties using high-performance liquid chromatography-quadrupole, time-of-flight, tandem mass spectrometry (HPLC-qTOF-MS/MS) analysis

Biochem/physiol Actions

(−)-Gallocatechin (GC) exerts antioxidant properties by scavenging free radicals. It can also inhibit osteoclastgenesis. GC elicits antimutagenic activity in Escherichia coli against ultraviolet (UV)-induced mutation. It also displays an inhibitory effect on the growth and adherence of Porphyromonas gingivalis in the buccal epithelial cells.

Other Notes

Polyphenolic compound found in green tea. An epimer of (−)-epigallocatechin.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers.

Q Guo et al.

Biochimica et biophysica acta, 1427(1), 13-23 (1999-03-20)

The purpose of this study is to examine the relationship between the free radical scavenging activities and the chemical structures of tea catechins ((-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and (-)-epicatechin (EC)) and their corresponding epimers ((-)-gallocatechin gallate (GCG), (-)-gallocatechin (GC)

Simultaneous analysis of individual catechins and caffeine in green tea

Goto T, et al.,

Journal of Chromatography A, 295-299 (1996)

Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism.

Chun Hay Ko et al.

Journal of agricultural and food chemistry, 57(16), 7293-7297 (2009-08-06)

In this study, three tea catechins, epigallocatechin (EGC), gallocatechin (GC), and gallocatechin gallate (GCG), were investigated for their effects on bone metabolism. The effects of the tea catechins on bone formation were evaluated using cultured rat osteoblast-like osteosarcoma cell line

Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis.

S Sakanaka et al.

Bioscience, biotechnology, and biochemistry, 60(5), 745-749 (1996-05-01)

Effects of polyphenolic compounds isolated from green tea (Camellia sinensis) on the growth and adherence of Porphyromonas gingivalis onto human buccal epithelial cells were investigated. Green tea polyphenols, especially (-)-epigallocatechin gallate (EGCg) which is a dominant component of tea polyphenols

Rapid Screening α-Glucosidase Inhibitors from Natural Products by At-Line Nanofractionation with Parallel Mass Spectrometry and Bioactivity Assessment.

Ruijie Liu et al.

Journal of chromatography. A, 1635, 461740-461740 (2020-12-04)

In this study, a novel at-line nanofractionation screening platform was successfully developed for the rapid screening and identification of α-glucosidase inhibitors from natural products. A time-course bioassay based on high density well-plates was performed in parallel with high resolution mass

모든 관련된 서류 보기

문서

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

(−)-Gallocatechin

≥98% (HPLC)

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

InChI

SMILES string

InChI key

assay

solubility

application(s)

storage temp.

Quality Level

관련 카테고리

설명

General description

Application

Biochem/physiol Actions

Other Notes

안전성 정보

pictograms

signalword

hcodes

pcodes

Hazard Classifications

target_organs

저장 등급

wgk

flash_point_f

flash_point_c

ppe

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