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I8280

Indomethacin

Name: Indomethacin
Brand: SIGMA

meets USP testing specifications

동의어(들):

1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₉H₁₆ClNO₄

CAS 번호:

53-86-1

Molecular Weight:

357.79

UNSPSC Code:

12352101

NACRES:

NA.21

PubChem Substance ID:

24896136

EC Number:

200-186-5

Beilstein/REAXYS Number:

497341

MDL number:

MFCD00057095

기술 서비스

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도움 문의

속성

Quality Level

200

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0%

form

powder

mode of action

enzyme | inhibits

SMILES string

COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3

InChI

1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)

InChI key

CGIGDMFJXJATDK-UHFFFAOYSA-N

Gene Information

human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689), Ptgdr(19214), Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219), Ptgs1(19224), Ptgs2(19225)
rat ... Alox5(25290), Ptgs1(24693), Ptgs2(29527)

설명

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.

Used as a non-selective inhibitor of cyclooxygenases, COX1 and COX2, leading to reduced prostaglandin biosynthesis from arachidonic acid.

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pictograms

GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 1 Oral

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

pcodes

P264 - P270 - P301 + P310 - P405 - P501

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