L9650
Lithium chloride
Molecular Biology, ≥99%
동의어(들):
LiCl
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
LiCl
CAS 번호:
Molecular Weight:
42.39
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-212-3
MDL number:
Assay:
≥99%
Grade:
Molecular Biology
Form:
powder
Solubility:
H2O: 100 mg/mL at 20 °C, clear, colorless
InChI key
KWGKDLIKAYFUFQ-UHFFFAOYSA-M
InChI
1S/ClH.Li/h1H;/q;+1/p-1
SMILES string
[Li+].[Cl-]
grade
Molecular Biology
assay
≥99%
form
powder
mp
605 °C (lit.)
solubility
H2O: 100 mg/mL at 20 °C, clear, colorless
anion traces
sulfate (SO42-): ≤0.01%
cation traces
Ba: ≤0.003%, Fe: ≤0.001%, K: ≤0.01%, Na: ≤0.20%, heavy metals (as Pb): ≤0.002%
foreign activity
DNase, NICKase, RNase, protease, none detected
Quality Level
유사한 제품을 찾으십니까? 방문 제품 비교 안내
Application
Lithium chloride has been used:
- in the preparation of wash buffer for chromatin immunoprecipitation
- in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
- to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling
May be used to selectively precipitate RNA.
Biochem/physiol Actions
Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
저장 등급
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells
Lacazette E
Biochemistry and Molecular Biology Education, 45(2), 152-160 (2017)
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
Vertino AM, et al.
Molecular Biology of the Cell, 16(4), 2039-2048 (2005)
mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms
Liu R, et al.
Molecular and cellular biology, 28(23), 7236-7244 (2008)
Daniel I Perez et al.
Journal of medicinal chemistry, 54(12), 4042-4056 (2011-04-20)
Development of kinase-targeted therapies for central nervous system (CNS) diseases is a great challenge. Glycogen synthase kinase 3 (GSK-3) offers a great potential for severe CNS unmet diseases, being one of the inhibitors on clinical trials for different tauopathies. Following
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