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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HO2CCH2CH(OH)CO2H
CAS 번호:
Molecular Weight:
134.09
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
EC Number:
202-601-5
MDL number:
Beilstein/REAXYS Number:
1723541
Assay:
≥95% (titration)
Form:
powder
assay
≥95% (titration)
form
powder
pKa (25 °C)
(1) 3.46, (2) 5.10
mp
101-103 °C ((lit.)), 101-103 °C (lit.)
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless
density
1,595 g/cm3 at 68 °F
Quality Level
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General description
L-Malic acid is the naturally occurring isomer of malic acid, found mainly in sour and unripe fruits.
Application
L-(-)-Malic acid may be used to prepare:
- diethyl (S)-malate
- ethyl (R)-2-hydroxyl-4-phenylbutanoate
- ethyl (S)-2-hydroxyl-4-phenylbutanoate
- D-homophenylalanine ethyl ester hydrochloride
- furo[3,2-i]indolizines
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A stereospecific synthesis of (-)-Bestatin from L-malic acid.
Norman BH and Morris ML.
Tetrahedron Letters, 33(45), 6803-6806 (1992)
Asymmetric synthesis of furo [3, 2-i] indolizines from L-malic acid.
Lee YS, et al.
Tetrahedron, 55(15), 4631-4636 (1999)
A practical synthesis of ethyl (R)-and (S)-2-hydroxy-4-phenylbutanoate and D-homophenylalanine ethyl ester hydrochloride from L-malic acid.
Lin WQ, et al.
Tetrahedron Asymmetry, 12(11), 1583-1587 (2001)
Mc Murry JE
Organic Chemistry , Biological Approach (2016)
Elena Grossini et al.
PloS one, 10(4), e0124742-e0124742 (2015-04-17)
Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether levosimendan could modulate the cross-talk between apoptosis and autophagy in the liver is still a matter
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Enzymatic Assay of Fumarase
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