M9429
Menadione
meets USP testing specifications
동의어(들):
2-Methyl-1,4-naphthoquinone, Vitamin K3
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C11H8O2
CAS 번호:
Molecular Weight:
172.18
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-372-6
Beilstein/REAXYS Number:
1908453
MDL number:
InChI key
MJVAVZPDRWSRRC-UHFFFAOYSA-N
InChI
1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
SMILES string
CC1=CC(=O)c2ccccc2C1=O
biological source
synthetic (organic)
agency
USP/NF, meets USP testing specifications
assay
98.5-101.0% dry basis
form
solid
mp
105-107 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... NQO1(1728)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
General description
Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.
Application
Menadione has been used:
- to treat HL-60 cells as positive control for apoptosis for flow cytometry
- as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization
- to treat HaCaT cell line, for quantifying total and oxidised glutathione
Biochem/physiol Actions
Menadione is an oxidative stress inducer.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
The Transgenic Zebrafish Display Fluorescence Reflecting the Expressional Dynamics of Dihydrofolate Reductase
Chang WN, et al.
Zebrafish, 14(3), 223-235 (2017)
Proteomic profile of aminoglutethimide-induced apoptosis in HL-60 cells: role of myeloperoxidase and arylamine free radicals
Khan SR, et al.
Chemico-Biological Interactions, 239, 129-138 (2015)
Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation
Bauman BM, et al.
Free Radical Biology & Medicine, 124(3), 532-540 (2018)
Nutrient Requirements of Swine, 75-75 (1998)
Juan Lucas Argueso et al.
Genome research, 19(12), 2258-2270 (2009-10-09)
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