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Merck

P2658

Poly-L-lysine hydrochloride

suitable for cell culture, Mol wt 15,000-30,000

동의어(들):

L-Lysine hydrochloride homopolymer

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26
MDL number:
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제품 이름

Poly-L-lysine hydrochloride, mol wt 15,000-30,000

form

powder or solid

mol wt

15,000-30,000

technique(s)

cell culture | mammalian: suitable

color

white to light yellow

application(s)

cell analysis

storage temp.

−20°C

Quality Level

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Application

Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment.
Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.

Biochem/physiol Actions

L-Lysine is believed to prevent osteoporosis of bones, which is a characteristics of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Poly-L-lysine is considered as a biocompatible polymer and serves for the purpose of drug delivery across cell membrane. It is useful as one of the nanosized contrast agents in MRI (magnetic resonance imaging).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Archishman Ghosh et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(39), 19474-19483 (2019-09-12)
Membraneless organelles, corresponding to the droplet phase upon liquid-liquid phase separation (LLPS) of protein or protein-RNA mixtures, mediate myriad cellular functions. Cells use a variety of biochemical signals such as expression level and posttranslational modification to regulate droplet formation and
Primary culture of neural precursors from the ovine central nervous system (CNS)
A. H. Duitozz and T. Hevor
Journal of Neuroscience Methods, 131-140 (2001)
Multi-technique characterization of poly-L-lysine dendrigrafts-Cu(II) complexes for biocatalysis.
Rossi JC
Macromolecular Bioscience, 15(2), 275-290 (2015)
The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells
Sahare Mahesh
Reproductive medicine and biology, 14(1) (2015)
Dietary l-Lysine Prevents Arterial Calcification in Adenine-Induced Uremic Rats
Akihiro Shimomura
Journal of the American Society of Nephrology, 25(9), 1954-1965 (2014)

문서

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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