P3490
Ponasterone A
≥65%
동의어(들):
2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one, 25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C27H44O6
CAS 번호:
Molecular Weight:
464.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Form:
powder
Quality level:
biological source
synthetic (organic)
Quality Level
sterility
non-sterile
form
powder
concentration
≥65%
solubility
ethanol: soluble
shipped in
ambient
storage temp.
−20°C
SMILES string
CC(C)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H44O6/c1-15(2)6-7-23(31)26(5,32)22-9-11-27(33)17-12-19(28)18-13-20(29)21(30)14-24(18,3)16(17)8-10-25(22,27)4/h12,15-16,18,20-23,29-33H,6-11,13-14H2,1-5H3/t16-,18-,20+,21-,22-,23+,24+,25+,26+,27+/m0/s1
InChI key
PJYYBCXMCWDUAZ-JJJZTNILSA-N
Application
Ponasterone A has been used to induce the expression of human huntingtin (HTT).
Suitable as an inducer of ecdysone-inducible mammalian expression system.
Biochem/physiol Actions
Ponasterone A is an insect hormone, involved in regulating metamorphosis.
Ponasterone A is an analogue of ecdysone.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Miodrag Grbić et al.
Nature, 479(7374), 487-492 (2011-11-25)
The spider mite Tetranychus urticae is a cosmopolitan agricultural pest with an extensive host plant range and an extreme record of pesticide resistance. Here we present the completely sequenced and annotated spider mite genome, representing the first complete chelicerate genome.
Donya Tohidi-Esfahani et al.
Pest management science, 67(11), 1457-1467 (2011-05-20)
Certain bisacylhydrazine compounds such as tebufenozide (RH5992) have been shown to act as order-specific insecticides. Their compatibility with predatory Heteroptera, which are used as biological control agents, has also been demonstrated. However, the molecular mode of action of these ecdysone
Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system
McDonald J, et al.
British Journal of Pharmacology, 140(1), 61-70 (2003)
Toshiyuki Harada et al.
Journal of chemical information and modeling, 51(2), 296-305 (2011-02-01)
Insect growth is regulated by the orchestrated event of ecdysteroids and their receptor proteins. Agonists/antagonists of ecdysteroid receptor are predicted to disrupt normal growth, providing good candidates of new insecticides. A database of over 2 million compounds was subjected to
Hanife Esengil et al.
Nature chemical biology, 3(3), 154-155 (2007-01-24)
The zebrafish has emerged as a versatile model organism for biomedical research, yet its potential has been limited by a lack of conditional reverse-genetic tools. Here we report a chemically inducible gene expression technology that has orthogonality to vertebrate signaling
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