P7252
Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt
≥98% (enzymatic), powder
동의어(들):
2-(Phosphonooxy)-2-propenoic acid tri(cyclohexylammonium) salt, PEP-3CHA, Phosphoenolpyruvic acid tris(cyclohexylamine) salt
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C3H5O6P · 3C6H13N
CAS 번호:
Molecular Weight:
465.56
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
252-618-7
MDL number:
Beilstein/REAXYS Number:
3752336
제품 이름
Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt, ≥98% (enzymatic)
InChI key
MJKYGUXBFYGLLM-UHFFFAOYSA-N
InChI
1S/3C6H13N.C3H5O6P/c3*7-6-4-2-1-3-5-6;1-2(3(4)5)9-10(6,7)8/h3*6H,1-5,7H2;1H2,(H,4,5)(H2,6,7,8)
SMILES string
NC1CCCCC1.NC2CCCCC2.NC3CCCCC3.OC(=O)C(=C)OP(O)(O)=O
assay
≥98% (enzymatic)
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
−20°C
Quality Level
General description
Phospho(enol)pyruvic acid is a highly functionalized small molecule. It plays a major role in the metabolism.
Application
Phospho(enol)pyruvic acid tri(cyclohexylammonium) salt has been used:
- in the pyruvate kinase/lactate dehydrogenase enzyme kinetic assay
- in the reaction mixture to determine fructokinase activity of Zobellia galactanivorans
- in luminometry to determine the amount of ADP formed by measuring the increase in light output
Biochem/physiol Actions
Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.
Phospho(enol)pyruvic acid is significant in high-phosphate group-transfer function. PEP plays a major role in PEP:sugar phosphotransferase system (PTS) mediated phosphorylation and transport of carbohydrates across the bacterial membrane. It functions to generate natural phosphonates catalyzed by PEP mutase. It plays a key role in the peptidoglycan cell wall biosynthesis.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Determination of Fructokinase Activity from Zobellia galactanivorans
Groisillier A and Tonon T
Bio-protocol, 5(21), e1633-e1633 (2015)
Structural basis for kinase-mediated macrolide antibiotic resistance
Fong DH, et al.
Structure, 25(5), 750-761 (2017)
Secretion from dense granules
Methods in Molecular biology: Platelets and Megakaryocytes, volume 1, functional assays, 89-91 (2004)
Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes
Garcia-Alles LF and Erni B
European Journal of Biochemistry, 269(13), 3226-3236 (2002)
Jan Niemann et al.
Free radical biology & medicine, 102, 174-187 (2016-11-29)
Mitochondrial dysfunction affects liver metabolism, but it remains unclear whether this interferes with normal liver aging. We investigated several mitochondrial pathways in hepatocytes and liver tissue from a conplastic mouse strain compared with the control C57BL/6NTac strain over 18 months
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