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Merck

R3030

Risperidone

≥98% (HPLC), powder, antipsychotic

동의어(들):

R 64,766

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C23H27FN4O2
CAS 번호:
Molecular Weight:
410.48
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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제품 이름

Risperidone, ≥98% (HPLC), powder

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥5 mg/mL

originator

Johnson & Johnson

storage temp.

room temp

SMILES string

CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1

InChI

1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

InChI key

RAPZEAPATHNIPO-UHFFFAOYSA-N

Gene Information

General description

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autism.

Application

Risperidone has been used:
  • to study its effects on bone formation and differentiation
  • to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients
  • to reverse induced schizophrenia-like behavior in mice

Biochem/physiol Actions

Risperidone is an antipsychotic; serotonin-dopamine antagonist.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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Schizophrenia (2006)
Kaplan & Sadock's Concise Textbook of Clinical Psychiatry (2008)
Effect of risperidone on proliferation and apoptosis of MC3T3-E1 cells
Zheng L, et al.
Brazilian journal of medical and biological research, 52(3) (2019)