S2424
Stigmasterol
~95%
동의어(들):
3β-Hydroxy-24-ethyl-5,22-cholestadiene, 5,22-Stigmastadien-3β-ol, Stigmasterin
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C29H48O
CAS 번호:
Molecular Weight:
412.69
UNSPSC Code:
12352211
NACRES:
NA.77
PubChem Substance ID:
EC Number:
201-482-7
Beilstein/REAXYS Number:
2568182
MDL number:
assay
~95%
mp
165-167 °C (lit.)
solubility
chloroform: 50 mg/ml
SMILES string
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)/C=C/[C@@H](CC)C(C)C
InChI
1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
InChI key
HCXVJBMSMIARIN-PHZDYDNGSA-N
Gene Information
human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)
Application
Stigmasterol was used as a reference standard in determination of phytosterols in dietary supplements by gas chromatography and in frozen leaf samples of Arabidopsis thaliana by GC/MS.
Biochem/physiol Actions
Stigmasterol is a phytosterol with chemical structure similar to cholesterol. It exhibits anti-cancer, anti-pyretic, anti-inflammatory and immune-modulating effects. Stigmasterol decreases the expression of matrix metalloproteinases and reduced the degradation of cartilage in osteoarthritic rabbits.
Preparation Note
Stigmasterol yields clear, colorless solution in chloroform at 50 mg/ml.
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
프로토콜
Separation of Cholesterol; Brassicasterol; Campesterol; Stigmasterol; β-Sitosterol
Thomas Griebel et al.
The Plant journal : for cell and molecular biology, 63(2), 254-268 (2010-05-07)
Upon inoculation with pathogenic microbes, plants induce an array of metabolic changes that potentially contribute to induced resistance or even enhance susceptibility. When analysing leaf lipid composition during the Arabidopsis thaliana-Pseudomonas syringae interaction, we found that accumulation of the phytosterol
Poliana Guerino Marson Ascêncio et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 190543-190543 (2015-01-15)
Costus spiralis (Costaceae) is a species native to the Amazon region and is used in traditional medicine. The endophytic fungi used in this study were obtained from leaves of this plant. 13 strains were selected to obtain hydroethanolic extracts and
Wendy R Sorenson et al.
Journal of AOAC International, 89(1), 22-34 (2006-03-04)
In conjunction with an AOAC Presidential Task Force on Dietary Supplements, a method was validated for measurement of 3 plant sterols (phytosterols) in saw palmetto raw materials, extracts, and dietary supplements. AOAC Official Method 994.10, "Cholesterol in Foods," was modified