SML0006
CK-666
≥98% (HPLC), powder, Arp2/3 comple inhibitor
동의어(들):
2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide, CK 666, CK-0944666
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C18H17FN2O
CAS 번호:
Molecular Weight:
296.34
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
제품 이름
CK-666, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
DMSO: ≥25 mg/mL
storage temp.
2-8°C
SMILES string
Cc1[nH]c2ccccc2c1CCNC(=O)c3ccccc3F
InChI
1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)
InChI key
UXRKUKRXVWJFER-UHFFFAOYSA-N
Application
CK-666 may be used to study Arp2/3-mediated structural changes in cells.
Biochem/physiol Actions
CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation.
CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex.
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저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable