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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS 번호:
Molecular Weight:
119.12
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-774-1
MDL number:
Beilstein/REAXYS Number:
1721646
제품 이름
L-Threonine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
InChI key
AYFVYJQAPQTCCC-GBXIJSLDSA-N
InChI
1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
SMILES string
C[C@@H](O)[C@H](N)C(O)=O
biological source
non-animal source
agency
USP/NF, meets EP testing specifications, meets JP testing specifications, meets USP testing specifications
product line
BioXtra
assay
99.0-101.0%
form
powder
quality
meets EP, JP, USP testing specifications
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
256 °C (dec.) (lit.)
solubility
H2O: 1 g/10 mL, clear, colorless
application(s)
pharmaceutical (small molecule)
Quality Level
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General description
L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.
Application
L-Threonine has been used for the following :
- To study the effect of heat on homoserine kinase activity
- In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
- As a substrate to determine the L-threonine dehydrogenase activity
- To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine
Biochem/physiol Actions
L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulation of L-Threonine Dehydrogenase in Somatic Cell Reprogramming
Chuanchun Han
Stem Cells, 31(5) (2013)
Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells.
Gonzalez-Leal IJ
Biotechnol. Progress, 27(6), 1709-1717 (2011)
Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida
Patricia Calero
Biotechnology and Bioengineering, 115(3), 762-774 (2018)
Homoserine Kinase from Escherichia coli K-12: Properties,
Inhibition by L-Threonine, and Regulation of Biosynthesis
Inhibition by L-Threonine, and Regulation of Biosynthesis
J. THEZE
Journal of Bacteriology, 118(2), 577-581 (1974)
Systems metabolic engineering of Escherichia coli for L?threonine production.
Lee HK, et al.
Molecular Systems Biology, 3(1), 149-149 (2007)
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