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Merck

T8657

Trichloroacetic acid

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

동의어(들):

TCA

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
Cl3CCOOH
CAS 번호:
76-03-9
Molecular Weight:
163.39
UNSPSC Code:
41105319
NACRES:
NB.22
PubChem Substance ID:
24900550
EC Number:
200-927-2
Beilstein/REAXYS Number:
970119
MDL number:
MFCD00004177
Assay:
≥99%
Form:
powder or flakes (or crystals)
Grade:
electrophoresis grade

주요 문서

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InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

grade

electrophoresis grade

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99%

form

powder or flakes (or crystals)

technique(s)

electrophoresis: suitable

turbidity

≤3 NTU (1 g/ml)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: 1 g/mL, clear, colorless

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%, nitrate (NO3-): ≤0.002%, phosphate (PO43-): ≤5 ppm, sulfate (SO42-): ≤0.02%

cation traces

Fe: ≤0.0005%, heavy metals (as Pb): ≤0.002%

suitability

suitable for fixing solution (for IEF and PAGE gels)

application(s)

cell analysis

storage temp.

2-8°C

Quality Level

200

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관련 카테고리

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Trichloroacetic acid has been used:
  • for hydrolysis of DNA isolated from the cell
  • for precipitation of glutathione isolated from seminal plasma
  • as a fixative in microscopy

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H314,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

wgk

WGK 2

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

저장 등급

8A - Combustible corrosive hazardous materials

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시험 성적서(COA)

Lot/Batch Number
MKCP9101
MKCL5989
MKCH9317
MKCF1796
MKCD2336

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리 방문

Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method
Lee J, et al.
Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.], 28(11), 1017-1021 (2002)
Cryotherapy compared with trichloroacetic acid in treating genital warts.
Godley MJ
Sexually Transmitted Infections, 63(6), 390-392 (1987)
Teratogenic activity of trichloroacetic acid in the rat
Smith MK, et al.
Teratology, 40(5), 445-451 (1989)
Atmospheric pressure pulsed plasma induces cell death in photosynthetic organs via intracellularly generated ROS
Seol Y, et al.
Scientific reports, 7(1), 589-589 (2017)
Quantitation of DNA fragmentation with diphenylamine
Boraschi D and Maurizi G
Apoptosis-a laboratory manual of experimental methods, 153-161 (1998)
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