U2625
Uric acid
≥99%, crystalline
동의어(들):
2,6,8-Trihydroxypurine
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C5H4N4O3
CAS 번호:
Molecular Weight:
168.11
UNSPSC Code:
12352005
NACRES:
NA.55
PubChem Substance ID:
EC Number:
200-720-7
Beilstein/REAXYS Number:
156158
MDL number:
Assay:
≥99%
Form:
crystalline
InChI key
LEHOTFFKMJEONL-UHFFFAOYSA-N
InChI
1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
SMILES string
O=C1NC(=O)C2=C(N1)NC(=O)N2
assay
≥99%
form
crystalline
mp
>300 °C (lit.)
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Application
Uric acid has been used:
- in inducing hyperuricemia in mice
- as a component of digestion fluid for the simulation of in vitro human digestion model
- in selectivity test of the glucose sensor in sweat-based diabetes monitoring
Biochem/physiol Actions
Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.
저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy
Lee H, et al.
Nature Nanotechnology, 11(6), 566-566 (2016)
Reduction of Serum Uric Acid Associated with Attenuation of Renal Injury, Inflammation and Macrophages M1/M2 Ratio in Hyperuricemic Mice Model
HARYONO A, et al.
Kobe J. Med. Sci., 64(3), E107-E114 (2018)
Uric acid in plants and microorganisms: Biological applications and genetics-A review
Hafez RM, et al.
Journal of Advanced Research, 8(5), 475-486 (2017)
Serum uric acid: a risk factor and a target for treatment?
Feig DI, et al.
Journal of the American Society of Nephrology, 17(4), S69-S73 (2006)
Serum uric acid as a predictor of mortality and future exacerbations of COPD
Bartziokas K, et al.
The European Respiratory Journal, 43(1), 43-53 (2014)
문서
Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.
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