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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3CONHC6H4OH
CAS 번호:
Molecular Weight:
151.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2208089
InChI
1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
SMILES string
CC(=O)Nc1ccc(O)cc1
InChI key
RZVAJINKPMORJF-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
acetaminophen, paracetamol
manufacturer/tradename
USP
Gene Information
human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Acetaminophen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
Also, for use with USP monographs such as:
- Acetaminophen Tablets
- Acetaminophen Capsules
- Acetaminophen Suppositories
- Acetaminophen Oral Suspension
- Acetaminophen Oral Solution
- Acetaminophen and Caffeine Tablets
- Acetaminophen Extended-Release Tablets
Analgesic.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
저장 등급
11 - Combustible Solids
flash_point_f
364.3 °F - Pensky-Martens closed cup
flash_point_c
184.6 °C - Pensky-Martens closed cup
Acetaminophen
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(6), 38-38 (2020)
Acetaminophen tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 45-45 (2021)
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
Karel Allegaert et al.
Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
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