N-Phenyl-1-naphthylamine

Name: <I>N</I>-Phenyl-1-naphthylamine
Brand: SIAL

reagent grade, 98%

Sinónimos:

1-(N-phenylamino)naphthalene, N-(1-Naphthyl)aniline, NPN

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Fórmula lineal:

C₁₀H₇NHC₆H₅

Número CAS:

90-30-2

Peso molecular:

219.28

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

57646802

EC Number:

201-983-0

Beilstein/REAXYS Number:

2211174

MDL number:

MFCD00003878

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Nombre del producto

N-Phenyl-1-naphthylamine, reagent grade, 98%

InChI key

XQVWYOYUZDUNRW-UHFFFAOYSA-N

InChI

1S/C16H13N/c1-2-9-14(10-3-1)17-16-12-6-8-13-7-4-5-11-15(13)16/h1-12,17H

SMILES string

N(c1ccccc1)c2cccc3ccccc23

grade

reagent grade

assay

98%

form

solid

bp

226 °C/15 mmHg (lit.)

mp

60-62 °C (lit.)

λ_max

252 nm

Quality Level

100

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Application

N-Phenyl-1-naphthylamine can be used as fluorescent probe for the determination of critical micelle concentration of surfactants. N-Phenyl-1-naphthylamine was used in a method for determination of the concentration of organolithium and organomagnesium reagents. N-Phenyl-1-naphthylamine was used as hydrophobic probe to study the phase transitions of membrane lipids in whole cells .

Biochem/physiol Actions

N-Phenyl-1-naphthylamine turns fluorescent after binding to hydrophobic regions of cell membranes.

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H302,H317,H373,H410

pcodes

P260 - P273 - P280 - P301 + P312 - P302 + P352 - P314

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B - STOT RE 2

target_organs

Blood

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Enhanced Thermostability of Glucose Oxidase through Computer-Aided Molecular Design.

Xiaoyan Ning et al.

International journal of molecular sciences, 19(2) (2018-02-01)

Glucose oxidase (GOD, EC.1.1.3.4) specifically catalyzes the reaction of β-d-glucose to gluconic acid and hydrogen peroxide in the presence of oxygen, which has become widely used in the food industry, gluconic acid production and the feed industry. However, the poor

Detection of early lymphocyte activation by the fluorescent cell membrane probe N-phenyl-1-naphthylamine.

G M Halliday et al.

Journal of immunological methods, 28(3-4), 381-390 (1979-01-01)

N-phenyl-1-naphthylamine (NPN) becomes fluorescent after binding to hydrophobic regions of cell membranes. Rat and mouse lymphoid cell suspensions stained with NPN showed changes in fluorescence emission 30 min after stimulation with mitogen or antigen, detected by microfluorimetry. Incubation of NPN-labelled

Determination of the critical micelle concentration of surfactants using the fluorescent probe N-phenyl-1-naphthylamine.

Bergbreiter DE and Pendergrass E.

The Journal of Organic Chemistry, 46(1), 219-220 (1981)

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens.

Daniel Pletzer et al.

PLoS pathogens, 14(6), e1007084-e1007084 (2018-06-22)

With the antibiotic development pipeline running dry, many fear that we might soon run out of treatment options. High-density infections are particularly difficult to treat due to their adaptive multidrug-resistance and currently there are no therapies that adequately address this

Enhancing antibiotic activity: a strategy to control Acinetobacter infections.

Sasitorn Chusri et al.

The Journal of antimicrobial chemotherapy, 64(6), 1203-1211 (2009-10-29)

The emergence of antibiotic resistance has seriously diminished antibiotic efficacy and an increasing number of infections are becoming difficult to treat. One approach to the restoration of antibiotic activity is to administer them in conjunction with non-antibiotic compounds that depress

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N-Phenyl-1-naphthylamine