912212
NanoFabTx™ PLGA-micro
for synthesis of 10-30 um particles
別名:
NanoFabTx™ reagent kit, PLGA microparticle kit
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この商品について
NACRES:
NA.23
UNSPSC Code:
12161503
General description
NanoFabTx™ PLGA-micro for synthesis of 10-30 μm particle reagent kit is a formulation kit that includes the reagents, stabilizers, and protocol to synthesize poly(lactic-co-glycolic acid) (PLGA) microparticles 10-30 μm in size. This reagent kit can be used with the NanoFabTx™ Microfluidic - micro device kit (Cat.No. 911879).
Application
This NanoFabTx™ reagent kit is designed for the synthesis of 10-30 μm PLGA microparticles to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery. By following the protocol, the user can synthesize drug-encapsulating microspheres 10 μm in size, 30 μm in size, or any size in between. With our step-by-step instructions, the user can identify the ideal microparticle size and drug loading for their research application without the need for lengthy trial-and-error optimization. PLGA microparticles are an excellent drug delivery system for controlled drug release because microparticles offer better encapsulation efficiency including higher drug loading capacity and lower excipient loads than nanoparticles. PLGA is a biocompatible and biodegradable polymer and compatible with many different types of therapeutic molecules and is the most widely used synthetic polymer in precision oncology. PLGA is approved by the FDA for biomedical and pharmaceutical applications such as oncology and immuno-oncology.
Features and Benefits
- Step-by-step protocols developed and tested by our formulation scientists
- Flexible synthesis tool to create uniform and reproducible microparticles with low polydispersity
- Based on non-toxic, biodegradable polymers
- Enables microparticle formulation screening and optimization to select ideal particle size for enhanced drug loading and controlled release
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
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保管分類
12 - Non Combustible Liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
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pdsc
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prtr
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fsl
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ishl_indicated
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ishl_notified
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cart
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資料
フラッシュナノ沈殿（Flash NanoPrecipitation, FNP）は高充填ナノ粒子を作製する新たな方法として2003年に報告され、物のカプセル化から農薬の送達までさまざまな分野に影響を与えています。
NanoFabTx™プラットフォームは、すぐに使用できる製剤と粒子合成のためのマイクロ流体デバイスにより、薬剤開発を加速させます。
NanoFabTXキットは、mRNAや核酸用の脂質ナノ粒子やリポソームによる正確な薬物送達を可能にします。