920436
NanoFabTx™ PEG-PLA drug formulation screening kit
for synthesis of PEGylated nanoparticles
別名:
Microfluidics, NanoFabTx™ reagent kit, Nanoformulation, Nanoparticle kit, PEG-PLA
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この商品について
NACRES:
NA.23
UNSPSC Code:
12161503
Storage temp.:
2-8°C
Quality Level
description
Kit components :
PEGPLA-L-M (919942-500mg)
PEGPLA-H-M (919934-500mg)
Stabilizer-Nano (907766-5g), PEG-PLA drug formulation screening kit, for synthesis of PEGylated PLA nanoparticles
application(s)
advanced drug delivery
storage temp.
2-8°C
General description
NanoFabTx™ PEG-PLA drug formulation screening kit is a nanoformulation kit containing rationally selected PEGylated PLA polymers that have been used widely for controlled drug release of many different types of therapeutic molecules. The kit contains protocols for two different particle synthesis methods:
- A Nanoprecipitation protocol to prepare drug-encapsulated nanoparticles in standard laboratory glassware.
- A Microfluidics protocol using commercial platforms or syringe pumps.
Application
NanoFabTx™ PEG-PLA drug formulation screening kit enables users to encapsulate a wide variety of therapeutic drug molecules in specifically sized, biodegradable, PEGylated PLA nanoparticles. By simplifying the chemistry and providing an easy-to-use toolkit with step-by-step instructions, our NanoFabTx™ nanoformulation screening kit helps researchers achieve reproducible synthesis of drug encapsulating nanoparticles with narrow size dispersity, eliminating the need for lengthy trial-and-error optimization. Suitable for biomedical research applications such as oncology, immuno-oncology, gene delivery, and vaccine delivery, PEG-PLA nanoparticles, made using the NanoFabTx™ PEG-PLA drug formulation screening kit, are designed for maximizing the encapsulation of hydrophobic drugs to minimize the time and expensive wasted reagents of synthetic optimization.
Features and Benefits
- Includes tested protocols with step-by-step instructions for nanoprecipitation or microfluidics-based syntheses
- Requires minimal laboratory setup
- Optimized to achieve monodisperse, homogenously shaped, biodegradable, PEGylated PLA nanoparticles in any size between 60 and 100 nm
- Formulated to maximize the encapsulation of hydrophobic drugs
- Includes two different PEGylated PLAs
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
保管分類
10 - Combustible liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
920436-1KT: + 920436-BULK: + 920436-VAR:
jan
資料
フラッシュナノ沈殿（Flash NanoPrecipitation, FNP）は高充填ナノ粒子を作製する新たな方法として2003年に報告され、物のカプセル化から農薬の送達までさまざまな分野に影響を与えています。
NanoFabTx™プラットフォームは、すぐに使用できる製剤と粒子合成のためのマイクロ流体デバイスにより、薬剤開発を加速させます。
NanoFabTXキットは、mRNAや核酸用の脂質ナノ粒子やリポソームによる正確な薬物送達を可能にします。